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Mesothelioma and Asbestos Exposure

The people who use products containing asbestos are at risk of inhaling or ingesting asbestos fibers. These fibers penetrate the chest cavity's lining or abdomen, also known as the pleura and peritoneum.

Exposure to asbestos can result in a lifetime risk of malignant mesothelioma that is peritoneal or pleural. While the risk does appear to decrease after 40 years of exposure, even minimal exposure to asbestos is risky.

Age

The older a person gets when exposed, the higher the risk of developing mesothelioma. Mesothelioma is a form of cancer that affects the mesothelium which is a thin layer of tissue that surrounds major organs in the body. The cancerous cells multiply uncontrollably and form tumors. Mesothelioma is most often diagnosed in people who were exposed to asbestos either in their work or as a family member of someone who worked with asbestos.

Asbestos exposure can lead to mesothelioma because it causes irritation to the mesothelium. The lining of the lungs (pleura) is most affected by mesothelioma of the pleural region, but it can also affect the lining of the abdomen and peritoneum or the heart lining (pericardium).

Asbestos is a mineral that occurs naturally, is durable and heat-resistant. It was utilized for construction as insulation, construction, and for other industrial uses until the 1980s. During this time millions of Americans were either exposed to asbestos as a result of their jobs or being near an asbestos-exposed loved one.

When asbestos is disturbed it releases fibers into the air. They can be inhaled and they are too hard for the body to break down or process. The fibers could cause irritation and even cancer in the lungs if they become stuck.

Symptoms of mesothelioma usually do not show up until decades after asbestos exposure. The symptoms are similar to those of other types of cancer, and they can be fatal if not treated.

Mesothelioma is more common in men than women, and is most often diagnosed in those over 45. Those who are at the most risk of developing mesothelioma because asbestos exposure in the workplace include ship builders, miners railroad workers, and those who have handled or installed items that contain asbestos. Family members of these people are also at greater risk since asbestos could be absorbed into their clothing.

Smoking

The longer a person is exposed to asbestos, the greater their risk of developing mesothelioma. This is due to the lengthy latency time that can range between 20 and 60 year from first exposure until diagnosis. Mesothelioma can occur in different areas of the body based on the type and amount of asbestos. Pleural mesothelioma is a condition that affects the lung's lining cavity and the chest wall (the pleura). Peritoneal Mesothelioma is a condition that affects the lining of the abdomen, also known as the peritoneum.

Most often, people who have been exposed to radiation develop mesothelioma in the chest or lung. People who worked in the shipbuilding, power generation and construction sectors are the most at risk. However, mesothelioma is also able to develop in individuals who were exposed to asbestos in their homes or at school. This is due to the fact that children and spouses of workers who were exposed to asbestos could bring the fibers home on their clothes hair, skin and even their hair which can put them at risk of developing the disease.

People with mesothelioma are typically white and older than 65. They are also more likely to have a blue-collar occupation or military history. Asbestos was extensively used by the United States Navy and other branches of the military because of its resistance to flames. Millions of veterans were exposed to asbestos.

Mesothelioma can form when a person's DNA undergoes mutations, causing cells to multiply uncontrolled. This leads to the formation of tumors, which eventually turn into mesothelioma. The disease can affect the whole body but is most prevalent in the abdomen and chest.

Smoking does cause mesothelioma but it increases your risk by increasing the amount of asbestos you breathe in. Anyone who has been exposed to asbestos should quit smoking cigarettes.

Additionally, a person's mesothelioma treatment plan should involve a doctor who understands asbestos exposure and the risk factors for this cancer. A mesothelioma specialist can help determine the best treatment option for this rare cancer. The specialist will be able to determine whether a patient is eligible for immunotherapy or experimental treatments.

Asbestos Exposure

Asbestos is a natural mineral that is utilized in many different products including flooring, insulation, roofing and flooring. Workers who handle, manufacture or work on asbestos-containing products are at a high risk of exposure. Exposure to asbestos fibers in the air can cause illness and cancer.

Many asbestos-related illnesses are not diagnosed until it's too late due to a long time period between exposure and the development of symptoms. Mesothelioma, the most dangerous of asbestos-related diseases is not an exception. Mesothelioma symptoms may manifest between 20 and 60 years after exposure to asbestos.

The most frequent way that people are exposed to asbestos is through occupational exposure. Any job that involves asbestos handling or use include those in construction, manufacturing automotive mechanics, as well as electrical. However, people can also be exposed to asbestos through at-home activities, such as smoking cigarettes or the renovation of older homes that contain asbestos.

Inhalation of asbestos is the most common cause of mesothelioma. Asbestos fibers that are inhaled can travel into the lungs and irritate the lining called the pleura. This irritation can result in thickened patches of pleura (pleural plates) and fibrosis within the lung. As the disease progresses it may cause fluid accumulation in the chest cavity (pleural effusion) and ultimately to lung cancer. Mesothelioma can also affect the tissue of other organs including the heart and abdomen.

People who are exposed to asbestos while at work are at a higher risk of developing mesothelioma. But people who have an ancestor with mesothelioma or any other asbestos-related diseases are also at risk. The risk of asbestos exposure is increased if someone has had more than one job over the course of their lives. Smoking cigarettes doesn't increase the risk of mesothelioma, but it can make the illness worse for those who have been diagnosed. If you have an history of exposure to asbestos and are suffering from mesothelioma, quitting smoking can prolong your life and improve your treatment outcome. Inform your doctor if have been exposed to asbestos or notice any new symptoms such as abdominal pain or a shortness of breathing. They can prescribe medication or operate to treat the disease.

Genetics

Many cancers are genetically linked, meaning that a person’s genes may increase the chance of developing a specific disease. Mesothelioma however does not have a gene component. Instead asbestos exposure is the main cause.

Asbestos fibers may enter the body via swallowing or inhalation, and then stick to the linings of the abdomen, chest or heart. Over time the loose fibers could alter or damage the cells that comprise these tiny linings, which can result in the development of mesothelioma.

However it is not the case that every person exposed to asbestos will develop mesothelioma. Researchers believe that other factors can affect whether a person gets mesothelioma due to asbestos exposure. This includes a person's gender and age and their family history of mesothelioma and other diseases and whether they have other risk factors like smoking.

Men are more likely than women to develop mesothelioma. This could be due to the fact that men were more likely than women to have been exposed to asbestos at work. Also, it takes between 20 and 60 years for mesothelioma to be diagnosed following a person's initial exposure to asbestos.

Another risk factor for mesothelioma is an infected gene. In Read Homepage of two families with high mesothelioma rates scientists discovered that nearly all members of the family carried a defective gene on the short arm of chromosome 3 The gene is known as BAP 1 and regulates how calcium moves inside cells. If the gene is defective, this process is affected and calcium levels drop. This enables asbestos to transform healthy cells into cancerous ones and cause mesothelioma.

In addition an mutated gene in a person's immune system can increase the likelihood of developing mesothelioma from exposure to asbestos. The mutated gene results in the loss of white blood cells. These cells are responsible for fighting cancerous cells.





Other factors that can raise the risk of mesothelioma in a person include the kind of asbestos they were exposed to as well as their job. In addition the polio vaccine that was given to children in the 1940s and 1950s could increase the risk of mesothelioma in a person by exposing them to the cancer-causing SV40 virus.