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The BIOFIRE System and Your Immune System
The BIOFIRE System provides syndromic infectious disease testing, which allows healthcare providers to choose the right test the first time. Patients benefit from faster diagnoses and more targeted treatments. Clinicians benefit from improved stewardship for antibiotics. Labs improve efficiency and cost savings.
The BioFire FilmArray Pneumonia plus panel (PN panel) examines native sputum, endotracheal aspirate, and bronchoalveolar specimens (including mini-BAL) for 33 pathogens that are clinically relevant and antimicrobial resistance genes with semiquantitative results within an hour.
Respiratory
The burning of biomass, such as wood, plants and other organic materials produces gaseous pollutants and fine particles that adversely affect the respiratory system. Furthermore, the environmental issues caused by forest fires, like droughts, could be potentiated by climate change, thereby increasing their negative impacts on human health.
In the United States wildfire smoke is associated with hospitalizations caused by respiratory diseases like asthma, COPD, and lung cancer. This kind of air pollution also increases the risk of cardiovascular disease and is a major cause of the burden of disease among the most vulnerable populations.
Wildfires caused unhealthy levels of air pollution in numerous communities during the COVID-19 epidemic. However, the public health response to this environmental issue has been limited and largely focused on communicating regarding symptom management. This knowledge gap is alarming due to the fact that smoking and other sources of air pollution can cause health problems.
Researchers are now looking at how to best protect the public's health during future events of this nature. NIH funds research on this important public health issue through the BLUE CORAL and FIRE CORAL studies.
For the first time an prospective cohort study will examine long-term effects resulting from exposure to smoke from wildfires and other sources. FIRE CORAL recruits adult participants who are admitted to hospital for COVID-19 index episodes and who speak English or Spanish, but are not pregnant. The FIRE CORAL protocol includes a series of tests conducted in-person, objectively measuring pulmonary function testing and lung imaging as well as functional assessment.
The lungs are especially sensitive to the effects of smoke and other particles since they can trigger or exacerbate chronic respiratory conditions, such as emphysema and COPD, and increase the risk of developing pneumonia. Smoke exposure can cause adverse consequences for health. To lessen or stop these negative effects, avoid outdoor activities and wear the EPA "N95" mask. This mask is designed to catch fine particles.
Smoking cigarettes can cause irritation to the throat and eyes, and lead to an irritated nose. To minimize symptoms, drink lots of water and take medication to reduce inflammation, such as corticosteroids.
Bloodstream
Your bloodstream is at the forefront of fighting germs that invade your body. Dendritic cells are specialized cells that are like the fire department's call center; they take antigens (molecules that trigger an immune response) from invading germs and then release proteins that alert other white blood cells to fight them. Circulating total white blood cell counts, differentials and band cells were increased after firefighters' firefighting shifts, as compared to levels following strenuous physical exercise without fire-fighting.
Skin
As the wildfires in California produced smoke and ash into the air this past fall and winter dermatologists were concerned how this might affect the skin of people exposed to it. Maria Wei is a graduate student at the University of California, Irvine. She investigates how the extreme pollution from wildfires impacts the skin. Her research was published on April 22, 2012 in Scientific Reports.
Wei's study shows that the temperature changes of the skin dependent on the amount of time the body is exposed. It can take as long as two hours for the skin of an individual to reach its "flash point"--the place where it begins to burn and then turns to ash. It's crucial not to be close to a fire or campfire, and you should always wear protective clothing if you're outdoors in a humid or hot day.
Forest fires will continue to occur, despite the steps taken to prevent the spread of wildfires. Wei is forecasting that the number of people suffering the consequences of wildfires will increase as climate change causes more forests to burn. This means that more people will have to wear long sleeves and hats and also thick moisturizers.
The air pollution from wildfires can cause atopic dermatitis to the skin, which causes itchy skin in a lot of people. She claims that the particles in smoke can clog up pores which can cause skin irritation.
Another issue is the fact that atopic dermatitis is known to make people more sensitive to UV light, which can be aggravated by smoke from wildfires. This makes people more likely to seek out tanning salons and could cause them to tan with less protection than they should.
While a cold and fire facial can help lessen the effects of atopic dermatitis, it's not recommended for anyone with an open wound or a rash on their face. Patients who have active acne should be cautious If you're pregnant or breastfeeding it is recommended to stay clear of this treatment altogether. The IS Clinical Fire & Ice Facial is offered at Novuskin Las Vegas' premier membership MedSpa is a results-driven, intensive facial that bridges between the mild facelift and the peel, with no time off. It's designed to rejuvenate skin, improve rosacea, reduce the appearance of acne scars and fine lines, as well as stimulate cellular regeneration. It's an incredible treatment that will give you an energizing glow.
Infections
The human body is a multi-faceted system of organs and tissues that work together to guard us against infections. Infections can be caused by microorganisms like parasites, viruses, and bacteria which infect healthy cells and cause them to multiply in uncontrolled ways. Your immune system can react by exhibiting symptoms of illness. These symptoms could range from a stuffy or runny nose to a stomach upset however, they may also include a fever high or swollen glands. You may also experience a eruption. The type of infection and its location can affect the severity of your symptoms.
Infections spread in many ways however the most common are transmitted from person to person through droplets that linger in the air after coughing or sneezing. This is how bacterial infections like tuberculosis, strep, and meningococcal illness and viral infections, such as the common cold and influenza, spread. Certain bacterial infections, such as skin infections or sexually transmitted diseases (STIs) like Chlamydia and gonorrhea can be transmitted through direct contact with infected tissues or mucous surfaces or indirectly through contaminated surfaces. Certain infections caused by bacteria are transmitted by insects such as fleas, ticks, or mosquitoes.
The virus and the parasites are small enough to penetrate your bloodstream and infect your cells which can lead to serious diseases such as the common cold and AIDS. Fungi can cause a variety of skin ailments such as ringworm and athlete's foot. Some are a threat to the lungs and nervous system, like the rabies virus.
The BioFire PN Panel utilizes our innovative FilmArray technology to analyze an extensive list of pathogens involved in upper respiratory infections in sputum and samples of bronchoalveolar fluid. The kit includes an reagent pouch that houses all the necessary chemistry to perform reverse transcription PCR, nested multiplex testing and detection using a single machine. This is a simple solution that aids clinicians in identifying and treat patients suffering from several respiratory symptoms. visit this hyperlink has been granted an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high-complexity labs.
