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The use of lytic bacteriophages against established biofilms of Proteus mirabilis and Escherichia coli is described, whereby biofilm populations have been reduced successfully by three to four log cycles (99-999% removal). The prevention of biofilm formation on Foley catheter biomaterials following impregnation of hydrogel-coated catheter sections with a lytic bacteriophage has also been investigated. This has revealed an approximate 90% reduction in both P. mirabilis and E. coli biofilm formation on bacteriophage-treated catheters when compared with untreated Effects of porous carrier size on biofilm development, microbial distribution and nitrogen removal in microaerobic bioreactors. School of Chemical Engineering and Technology, Tianjin University, Collaborative Innovative Center of Chemical Science and Engineering (Tianjin), Tianjin 300072, Science and Engineering (BESE), King Abdullah University of Science and In this study, effects of porous carrier's size (polyurethane-based) on microbial characteristics were systematically investigated in addition to nitrogen removal performance in six microaerobic bioreactors.

Among different removal (98%) due to optimal micro-environments created for aerobic nitrifiers in outer layer (0-7mm), nitrifiers and denitrifiers in middle layer (7-10mm) and anaerobic denitrifiers in inner layer (10-15mm). Candidatus brocadia, a dominant anammox bacteria, was solely concentrated close to centroid (0-70μm) and strongly co-aggregated with other bacterial communities in the middle layer of the carrier. Contrarily, carriers with a smaller (<15mm) or larger size (>15mm) either destroy the effective zone for anaerobic denitrifiers or damage the microaerobic environments due to poor mass transfer. This study is of particular use for optimal design of carriers in enhancing simultaneous nitrification-denitrification in microaerobic wastewater treatment processes. Enhanced nitrogen and phosphorus removal from domestic wastewater via algae-assisted sequencing batch biofilm reactor. Get it now proposed a potential strategy for enhancement of nutrients removal from domestic wastewater by adding algae to sequencing batch biofilm reactor that the algae-assisted SBBR increased the total nitrogen and phosphorus removal carriers fixed at the top of the reactor were favorable for both formation of ABS system and algae enrichment. The chlorophyll-a increased to 39 mg/g at bio-carrier replacement and sludge discharge were independent, indicating that the sludge and algae retention time could be separated.

The mechanisms analysis suggested that the enhanced nitrogen and phosphorus mainly attributed to the enrichment of both algae biomass and total biomass in biofilm. This study highlights the significance of developing ABS system for wastewater treatment. Novel antibiofilm chemotherapies target nitrogen from glutamate and glutamine. Bacteria in nature often reside in differentiated communities termed biofilms, which are an active interphase between uni-cellular and multicellular life states for bacteria. Here we demonstrate that the development of B. subtilis biofilms is dependent on the use of glutamine or glutamate as a nitrogen source. https://willard-lambert-2.technetbloggers.de/aeruginosa-strains-faeces-mastitis-faeces-hospital-patients-environment show a differential metabolic requirement within the biofilm; while glutamine is necessary for the dividing cells at the edges, the inner cell mass utilizes lactic acid.

Our results indicate that biofilm cells preserve a short-term memory of glutamate metabolism. Finally, we establish that drugs that target glutamine and glutamate utilization restrict biofilm development. Overall, our work reveals a spatial regulation of nitrogen and carbon metabolism within the biofilm, which contributes to the fitness of bacterial complex communities. This acquired metabolic division of labor within biofilm can serve as a target for Conflict of interest statement: The authors declare no competing interests. Carbon dot-based therapeutics for combating drug-resistant bacteria and biofilm Joint Engineering Research Center of Storage, Processing and Safety Control Drug-resistant bacteria are caused by antibiotic abuse and/or biofilm formation and have become a threat to the food industry. Carbon dot (CD)-based nanomaterials are a very promising tools for combating pathogenic and spoilage bacteria, and they possess exceptional and adjustable photoelectric and chemical properties.